Origin of Life

Ulf Diederichsen

Last Event

10th June 2016, 16:15
Astrophysical Sources of Energy for Life



Ulf Diederichsen, born 1963, studied Chemistry in Freiburg with a diploma work in organic synthesis and completed his Ph.D. in 1993 under the supervision of Albert Eschenmoser at the ETH Zürich working on homo- and glucose-DNA. Following postdoctoral work on radical chemistry at the University of Pittsburgh in the group of Dennis Curran, he gained his habilitation at the Technical University Munich with Horst Kessler as mentor starting research on linear peptide nucleic acids as model system for pairing, stacking, electron transfer and recognition. In 1999 he was appointed professor of Organic Chemistry at the University Würzburg until joining Göttingen University in 2001 as full professor of Organic Chemistry. He was visiting professor at the LMU Munich and Goering Visiting Professor at the University of Wisconsin. In 1999 he got the Karl Winnacker stipend and Hellmut-Bredereck award and is an ordinary member of Göttingen Academy of Sciences and Humanities since 2012.


Selected papers


Hunziker J, Roth HJ, Böhringer M, Giger A, Diederichsen U, Göbel M, Krishnan R, Jaun B, Leumann C, Eschenmoser A (1993) Warum Pentose- und nicht Hexose-Nucleinsäuren? Teil III: Oligo(2’,3’-dideoxy-β-D-glucopyranosyl)nucleotide ('HOMO-DNS'): Paarungseigenschaften, Helv. Chim. Acta 76, 259 - 352.


Diederichsen U (1996) Pairing Properties of Alanyl Peptide Nucleic Acids Containing an Amino Acid Backbone with Alternating Configuration, Angew. Chem. 108, 458-461. Angew. Chem. Int. Ed. Engl. 35, 445-448.


Diederichsen U, Weicherding D, Diezemann N (2005) Side chain homologation of alanyl peptide nucleic acids: pairing selectivity and stacking, Org. Biomol. Chem. 3, 1058-1066.


Diederichsen U (2011) Lineare molekulare Architekturen mit DNA- und Peptid-Biooligomer-Gerüsten, in: Aus den Elfenbeintürmen der Wissenschaft, XLAB Science Festival, Band 5, E.-M. Neher (Ed.), Wallstein Verlag, Göttingen, pp. 111-123.


Lygina AS, Meyenberg K, Jahn R, Diederichsen U (2011) Transmembrane domain peptide/peptide nucleic acid hybride as SNARE protein model in vesicle fusion, Angew. Chem, 123, 8756-8760;. Angew. Chem. Int. Ed. 50, 8597-8601.

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